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. Author manuscript; available in PMC: 2013 May 7.
Published in final edited form as: Int J Neuropsychopharmacol. 2009 Dec 14;13(3):321–334. doi: 10.1017/S1461145709990630

Figure 4. Effects of acute and sub-chronic administration of citalopram on CREB activation in the hippocampus.

Figure 4

A) A single administration of Citalopram (10mg/kg, 30 min.) failed to increase CREB activation in the hippocampus (n=9-10). Values are means +/−SEM. B) Three administrations of citalopram over 24 hours of citalopram increased P-CREB/CREB ratio in the hippocampus (n=7-9). Values are means +/−SEM. * groups that differed significantly from respective saline treated animals (p<0.05).