Table 3.

Effectiveness of photodynamic therapy (PDT) with the use of the photosensitizer bacteriochlorin p conjugated to MNT (MNT–BChl)

Mouse melanoma	Number of PDT sessions (number of exposures per session)	Tumor growth inhibition, % relative to:		Lifespan since tumor inoculation, days (mean ± SE)
		control	Bchl	MNT-Bchl	Bchl	control
B16-F1	4 (3)	80	85	29±3*	18±3	18±3
	5 (1)	82	89	34±4*	18±1	20±3
Cloudman S91 (clone M3)	5 (1)	98	93	52±17**	35±10	21±2

Note: BChl—bacteriochlorin.

Differences from the respective group “BChl” were significant at

^*p < 0.002 and

^**p < 0.05 (according to the Mantel–Hansel test).