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. Author manuscript; available in PMC: 2014 Apr 2.
Published in final edited form as: Breast Cancer Res Treat. 2013 Apr 2;138(3):807–816. doi: 10.1007/s10549-013-2504-3

Figure 3. Manhattan plots depicting associations between candidate SNPs and treatment discontinuation using a recessive statistical model.

Figure 3

Figure 3

Dashed line signifies level of statistical significance after Bonferroni correction (p=0.00036). AIMSS: Aromatase inhibitor-associated musculoskeletal syndrome; HR: hazard ratio. A. Treatment discontinuation because of AIMSS for patients treated with exemestane. B. Treatment discontinuation because of any toxicity for patients treated with exemestane.