Figure 4. fAd and gAd alter the ultrastructure of tight junctions in the perfused submandibular glands.
Representative images of tight junctions in submandibular glands without (A), or with KRH (B), 5 μg/ml fAd (C), 1 μg/ml gAd (D), or 1 mM AICAR (E) perfusion. The glands were pre-perfused with 1 mM AraA, then followed by fAd (F), gAd (G), or AraA alone (H). Tight junctions were showed with arrows. Bar: 200 μm. (I) The width of apical tight junctions was measured from 4 sections of 10 random fields in the above 8 groups. Values are means ± SD from 4 independent experiments. *P<0.05 compared with KRH group.