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. 2013 May 7;8(5):e60850. doi: 10.1371/journal.pone.0060850

Figure 1. Effect of U50,488H on mPAP, RVP and RVHI in rats exposed to chronic hypoxia for 2 wk.

Figure 1

A, group results for mPAP; B, group results for RVP; C, group results for RVHI; Values are means ± SE. n = 8. Con: Control (normoxic group); 2 w: hypoxia for 2 wk; NS: normal saline; U50: U50,488H (1.25 mg/kg); nor-BNI: nor-Binaltorphimine (2.0 mg/kg); mPAP: mean pulmonary artery pressure; RVP: right ventricular pressure; RVHI: right ventricular hypertrophy index. RV: right ventricle; LV: left ventricle; S: septum; BW: body weight. *P<0.05, **P<0.01 vs. control; # P<0.05, ## P<0.01 vs. 2 w group; § P<0.05, §§ P<0.01 vs. 2 w+NS group; τ P<0.05, ττ P<0.01 vs. 2 w+U50,488H group.