Peripheral T cells in T cell-specific NF1-deficient TCR Tg mice. All experiments were performed with littermate Nf1flfl and Nf1fl/fl plck-cre HY TCR Tg or AND TCR Tg mice. Histograms show representative CD44 staining upon gated HY or AND TCR+ T cells in spleens. Bar graphs show the mean number plus 1 SEM of total, CD44lo and CD44hi HY or AND TCR+ splenocytes. HY Tg female (Nf1fl/fl, n=9; Nf1fl/fl plck-cre, n=11), HY Tg male (Nf1fl/fl, n=9; Nf1fl/fl plck-cre, n=10), AND Tg (Nf1fl/fl, n=3; Nf1fl/fl plck-cre, n=3).