Figure 2.
Depletion of FBXW7 in HCT116 cells enhances cell migration and invasion. (A) Migration of HCT116 FBXW7−/− and its control cells was measured by wound healing assay. (B) Migration and invasion ability of HCT116 FBXW7−/− and its control cells were determined by uncoated or Matrigel-coated transwell assay. Data were presented as means ± Standard deviation from three independent experiments in triplicates. *P < 0.05 and **P < 0.01 were obtained from Student’s t-test.