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. Author manuscript; available in PMC: 2014 May 3.
Published in final edited form as: Biochem Biophys Res Commun. 2013 Apr 2;434(2):352–356. doi: 10.1016/j.bbrc.2013.03.077

Figure 4.

Figure 4

Rapamycin alleviates the enhanced migration, invasion and stemness induced by depletion of FBXW7. Wound healing assay (A), uncoated (B) or Matrigel-coated (C) transwell assay of HCT116 FBXW7−/− cells treated with DMSO control or Rapamycin. (D) Number of spheres was quantified using sphere formation assay for 104 HCT116 FBXW7−/− cells treated with DMSO control or Rapamycin. Data were presented as means ± Standard deviation from three independent experiments in triplicates. **p < 0.01 was based on Student’s t-test.