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. 2013 May 7;8(5):e62154. doi: 10.1371/journal.pone.0062154

Figure 3. TSCC shows increased Tc22 and decreased Th1 polarization.

Figure 3

T cell “crawl outs” were activated and intracellular cytokines stained. Live CD3+CD4+ and CD3+CD8+ cells were gated, and then frequencies of the cells producing indicated cytokines were analyzed. (a) Representative dot plot analysis of IFN-γ, IL-4, IL-17, and IL-22 expression in CD4+ and CD8+ T cells from SCC specimens. Numbers indicate percent gated cells. (b) Summary results from 20 SCC and 12 TSCC patients. The Mann-Whitney U-test was used for the statistical comparison between two groups. Asterisks (*) indicate statistical significance (p<0.05).