Table 1. Patient and Tumor Characteristics.

Characteristics	Value	Hazard Ratio per unit change (95% CI)	P
Patient Age		0.974 (0.935–1.027)	0.2
<50	38
> = 50	25
Pretreatment Tumor Size
Longest diameter (median, interquartile range in cm)	5.12 (3.44–7.66)	1.220 (1.059–1.405)	0.006
Volume measured by MRI (median, interquartile range in cm3)	16.5 (5.77–43.1)	1.017 (1.006–1.027)	0.002
Pathologic tumor size at resection (median, interquartilerange in cm) (n = 62, 1 missing)	2.50 (1.30–5.33)	1.164 (1.018–1.331)	0.03
Nodal Status (n = 62)
No. positive nodes (median, interquartile rage)	1 (0–4)	1.074 (1.010–1.141)	0.03
Patients with positive nodal involvement	40
Patients without positive nodal involvement	22
Pathology Class (analyzed as continuous)*
No. Patients		1.387 (0.856–2.246)	0.2
Class 1 = No residual disease or pCR	7
Class 2 = <1 cm residual disease	5
Class 3 = 1 cm <residual disease <2.5 cm	19
Class 4 = >2.5 cm residual disease	30
Scharff-Bloom-Richardson grade (n = 51) (analyzed as continuous)*		1.206 (0.912–1.597)	0.2
No. Patients
1	13
2	21
3	17