Table 1. Patient characteristics for cases assessed by bisulfite pyrosequencing.

Parameter	Controls n = 111	EOPET n = 19	LOPET n = 18	nIUGR n = 13
Birth weight (g)	2590±989	1399±621	2742±798	2132±513
Birth weight (SD)	0.06±0.07	−1.51±0.22***	−0.73±0.29**	−1.67±0.20***
Co-existing IUGR	–	14/19	5/18	–
Gestational age (weeks)	35.09±4.21	31.93±3.27*	37.47±2.29*	36.43±2.31
Maternal age (years)	33.10±4.74	34.16±6.01	33.49±5.47	34.64±5.26
Female: Male ratio	55∶56	7∶12	10∶8	9∶4
Mode of delivery
Labour	46	4	9	5
No Labour	8	6	3	4
Undefined	57	9	6	4

Birth weight statistics are based on standard deviation (SD) points relative to gestational age and gender matched normal birth weight ranges. Gestational age values are given at birth. Data are mean ± SD. The mode of delivery is characterised as ‘Labour’ (spontaneous or induced vaginal delivery), ‘No Labour’ (elective caesarean section) or, ‘Undefined’: emergency caesarean section or unknown. EOPET: early onset pre-eclampsia, LOPET: late onset pre-eclampsia, nIUGR: normotensive intrauterine growth restriction,

^* P<0.05,

^** P<0.01,

^*** P<0.001, compared to controls.