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. 2013 Mar 11;89(3):118–128. doi: 10.2183/pjab.89.118

Figure 3.

Figure 3.

Gata4/Mef2c/Tbx5 Induce cardiac gene expression in fibroblasts. Immunofluorescent staining for αMHC-GFP (green), α-actinin (red) and DAPI (blue). In the negative control (control), cardiac genes were not induced. The combination of three factors, Gata4/Mef2c/Tbx5 (GMT), induced abundant αMHC-GFP and α-actinin expression in fibroblasts. High-magnification views in insets showed sarcomeric organization.14)