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. 2013 Apr 16;2:165. doi: 10.1186/2193-1801-2-165

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© Mizunoya et al.; licensee Springer. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effect of long term feeding (4 weeks) of a particular diet containing different dietary fats (soybean oil, lard, or fish oil) on the anxiety-like behavior in the elevated plus-maze test. Mouse behavior was tested for a 10-min interval in the elevated plus-maze. Increase of the time in open arms (A) is considered an anxiolytic index, whereas the total moving distance (B) is considered an index of general locomotor activity. Values are means ± SE for 12 mice per group. Significantly different between 2 groups (*p < 0.05, by Tukey-Kramer multiple comparison test). P-values by one-way ANOVA are shown above each graph.