Table 1.
Trans monolayer |
|||||
---|---|---|---|---|---|
DOBMP− | DPhPC | DOTAP+ | |||
Cis monolayer | DOBMP− | Control | 0.06 ± 0.036 pA | 0.09 ± 0.05 pA | 0.08 ± 0.04 pA |
R9C 10 μM | 0.06 ± 0.04 pA | 0.10 ± 0.06 pA | 0.075 ± 0.04 pA | ||
DPhPC | Control | 0.12 ± 0.07pA | 0.15 ± 0.055 pA | 0.13 ± 0.06 pA | |
R9C 10 μM | 0.09 ± 0.06 pA | 0.12 ± 0.06 pA | 0.13 ± 0.05 pA | ||
DOTAP+ | Control | 0.08 ± 0.04 pA | 0.13 ± 0.06 pA | 0.23 ± 0.06 pA | |
R9C 10 μM | 0.07 ± 0.04 pA | 0.13 ± 0.06 pA | 0.25 ± 0.06 pA |
Transmembrane currents through bilayers formed over a ∼70 μm diameter aperture in 0.15 M CsCl were measured in the absence and presence of oligoarginine from the cis side at 100 mV applied voltage. Standard error was calculated from 3 to 4 experiment replications.