Figure 5.

(A) Histograms of the Cohen's d effect sizes. Blue bars indicate the effect sizes obtained in the 15-month period; orange bars indicate effect sizes obtained in the current study in the 6-month period between the 15-month and 21-month endpoints. Green bars indicate effect sizes that were calculated based on the neuropsychological data in Stout et al.²¹. Note that for the Stout et al.²¹ data, the direction of longitudinal performance development is not coded. (B) Cohen's d effect sizes were normalized monthly. Normalization was calculated on the basis of the 15-month longitudinal data (this study) and the 12-month longitudinal data from the Stout et al.²¹ study.