Figure 1.

Composition of the ileum microbiome characterized in the control subject and in the Crohn's disease (CD) patient before therapy (patient-BT) and after therapy (patient-AT) by next-generation sequencing of the 16S rRNAs. (a) Phylum-level classification shows the reduction of Bacteroidetes and the significant prevalence of Proteobacteria in the patient-BT vs. the control and the patient-AT. (b) The heatmap table highlights in brownish red the most significant alterations in the bacterial composition of gut microbiome detected in the CD patient-BT; the numerical figures indicate the number of bacterial families sequenced in each patient.