Table 2.

Unadjusted and Adjusted 3‐Year Hazard Ratio for MACE at 3 Years Stratified by Optimal Cut‐Off Values for Serum Arylesterase and Paraoxonase Activity Levels

	Arylesterase activity, μmol(L·min) per mL (range)		Paraoxonase activity, nmol(L·min) per mL (range)
Range	<70	≥70	<280	≥280
3‐y MACE, %	41/107	125/523	52/161	114/469
Unadjusted HR	1.80 (1.26 to 2.57)**	1	1.35 (0.98 to 1.88)	1
Adjusted HR	1.55 (1.08 to 2.23)*	1	1.22 (0.87 to 1.71)	1

Model adjusted for traditional risk factors including age, sex, systolic blood pressure, low‐density lipoprotein cholesterol, high‐density lipoprotein cholesterol, smoking, diabetics, and ACE inhibitor, ARB, β‐blocker, and statin use. MACE indicates major adverse cardiac events; HR, hazard ratio; ACE, angiotensin‐converting enzyme; ARB, angiotensin II receptor blocker. *P<0.05, **P<0.01.