Table 2.
Cox Proportional Regression Analyses for All‐Cause Mortality
| Variable | Planned Model* HR (95% CI) | P Value | Extended Model* HR (95% CI) | P Value |
|---|---|---|---|---|
| Anxiety | 1.83 (1.18 to 2.83) | 0.006 | 1.79 (1.15 to 2.78) | 0.010 |
| Depression | 1.66 (1.06 to 2.58) | 0.025 | 1.31 (0.82 to 2.05) | 0.27 |
| Age tertile | 1.66 (1.32 to 2.09) | <0.001 | 1.83 (1.45 to 2.32) | <0.001 |
| CHF | 2.44 (1.62 to 3.68) | <0.001 | 2.15 (1.42 to 3.28) | <0.001 |
| 3‐Vessel CAD | 1.78 (1.24 to 2.54) | 0.002 | 1.85 (1.29 to 2.65) | <0.001 |
| LVEF | 0.99 (0.97 to 1.00) | 0.063 | 0.99 (0.97 to 1.00) | 0.065 |
| Renal disease | 2.22 (1.51 to 3.27) | <0.001 | 2.19 (1.46 to 3.28) | <0.001 |
| ICD | — | 5.49 (3.23 to 9.33) | <0.001 | |
| Antidepressant use | — | 1.90 (1.29 to 2.80) | 0.001 | |
| Insulin | 1.59 (1.06 to 2.38) | 0.025 |
HR indicates hazard ratio; CI, confidence interval; CHF, congestive heart failure; CAD, coronary artery disease; LVEF, left ventricular ejection fraction; ICD, implantable cardioverter defibrillator.
*
Adjusted for age tertile, CHF, presence of 3‐vessel disease, left ventricular ejection fraction, and renal disease (end‐stage renal disease and chronic renal insufficiency).
*
Adjusted for the variables in the a priori planned model, as well as presence of an internal cardioverter defibrillator, antidepressant use, and insulin use.