Table 2.
Paired Replicate Rescan Estimates of Variability of the Different Plaque Metrics in the Multi‐Ethnic Study of Atherosclerosis
Methods of Estimating Plaque | Value | Lower 95% CI | Upper 95% CI | No. of Replicate Values | Measure of Agreement/Association |
---|---|---|---|---|---|
Any plaque (>0%) | 0.886 | 0.854 | 0.919 | 144 | κ |
Plaque (≥25%) | 0.833 | 0.793 | 0.874 | 144 | κ |
Maximum internal carotid artery IMT*, mm | 0.908 | 0.874 | 0.933 | 141 | Pearson |
Combined subjective and far wall IMT >1.5 mm | 0.944 | 0.917 | 0.971 | 144 | κ |
Maximum ICA IMT (>1.5 mm)* | 0.870 | 0.836 | 0.904 | 141 | κ |
Mean of the maximum ICA IMT, mm | 0.897 | 0.859 | 0.925 | 141 | Pearson |
Examinations were blindly reread after blinded replicate scans. Because of the blinded nature of the replicate scanning protocol, the same reader was likely to reread the replicate examination. From a total of 151 blinded rescans and then blinded interpretations, 144 were from the same readers. ICA indicates internal carotid artery; IMT, intima‐media thickness.
Measurements were not obtained for the ICA IMT in 3 of the 144 replicate studies.