Table 5.

Respective HRs, Change in C‐Statistic, NRI and IDI for Coronary Heart Disease Events When Each Plaque Metric Is Added to a Baseline Model With Risk Factors Shown in Table 3

Variable	HR	HR Lower 95% CI	HR Upper 95% CI	P‐Value	Change in C‐Statistic	Lower 95% CI	Upper 95% CI	P‐Value	NRI (%)	P‐Value	IDI	P‐Value
Plaque >0%	1.67	1.33	2.10	<0.001	0.0089	0.0005	0.0173	0.037	4.2	0.035	0.0035	<0.001
Plaque ≥25%	1.67	1.30	2.13	<0.001	0.0078	0.0012	0.0145	0.021	5.0	0.0053	0.0037	0.003
Maximum of the ICA IMT, mm	1.27	1.18	1.38	<0.001	0.0123	0.0042	0.0203	0.003	6.8	0.0005	0.0074	<0.001
Plaque or maximum of the far wall IMT >1.5 mm	1.77	1.40	2.25	<0.001	0.0111	0.0018	0.0204	0.019	4.7	0.032	0.0045	<0.001
Maximum of the ICA IMT >1.5 mm	1.80	1.42	2.27	<0.001	0.0109	0.0014	0.0205	0.025	3.9	0.062	0.0053	<0.001
Mean of the maximum ICA IMT, mm	1.43	1.26	1.63	<0.001	0.0131	0.0056	0.0207	0.001	7.0	0.0003	0.0035	<0.001

HR indicates hazard ratio; NRI, net reclassification improvement; IDI, integrated discrimination improvement; ICA, internal carotid artery; IMT, intima‐media thickness.