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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Placenta. 2013 Apr 17;34(6):497–502. doi: 10.1016/j.placenta.2013.03.008

Table 2.

AT1, AT2 and AT1-7 Receptors Binding in the Uterus of Virgin and the Uterus and Placenta of Normal Pregnant and RUPP 19-day Sprague-Dawley Rats.

Uterus or Uteroplacental Unit AT1R % competition with losartan AT2R % competition with PD1233195 Mas/AT1-7R % competition with D-Ala
Virgin Endometrium 94 ± 3* 28 ± 11# 25 ± 7#
Myometrium 92 ± 4* 20 ± 11 18 ± 4#
Pregnant Mesometrial triangle 90 ± 5 7 ± 7 22 ± 15
Labyrinth placenta 98 ± 1 20 ± 11 14 ± 8
RUPP Mesometrial triangle 96 ± 2 7 ± 4 13 ± 7
Labyrinth placenta 99 ± 1 7 ± 5 13 ± 5#

Values represent % of total binding. AT1, AT2 and mas/AT1-7R values represent % competition with 3 μM of losartan, PD123319 and D-Ala7-Ang-(1-7) respectively. AT1R values were compared with the constant 100% to determine whether the AT1R subtype accounted for all binding observed. Values for AT2R and mas/AT1-7R were compared with the constant 0% to determine whether there was a significant contribution of AT2R and mas/AT1-7R to the total binding.

*

p<0.05 vs. 100%;

#

p<0.05 vs. 0%; n = 9–11.