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. Author manuscript; available in PMC: 2013 May 8.
Published in final edited form as: Exp Parasitol. 2012 Oct 22;133(1):28–36. doi: 10.1016/j.exppara.2012.10.002

Table 1.

Distribution of shared glycotopes expressed on hemocytes from the susceptible (NMRI) and resistant (BS-90) strains of Biomphalaria glabrata. Treatment of hemocytes with larval transformation products (LTPs) significantly modulates expression of shared glycans as determined by reactivity to specific anti-glycan monoclonal antibodies. Prevalence data represent the mean ± S.D. of 3–6 independent replicates. Significance levels were set at α < 0.05 (2-factor ANOVA; see Results)

Glycotope Prevalence Reactive Hemocytes (%)

No LTP Treatment LTP Treatment

NMRI BS-90 NMRI BS-90

TriMan 83.7 ± 3.1 92.6 ± 2.1 87.1 ± 5.2 89.6 ± 1.6
F-LDN-F 83.7 ± 6.5 89.2 ± 5.2 83.4 ± 7.1 90.0 ± 1.2
F-LDN 53.2 ± 5.0 77.4 ± 10.4* 55.6 ± 7.8 77.7 ± 7.3*
LDN 0.0 0.0 23.2 ± 7.7! 46.6 ± 8.3! *
LDN-F 3.7 ± 1.3 3.0 ± 4.1 45.9 ± 13.6! 48.0 ± 11.5!
LDN-DF 0.0 0.0 15.5 ± 2.5! 22.9 ± 5.1!
LeX 2.8 ± 3.4 1.6 ± 3.5 4.7 ± 5.5 7.4 ± 1.4
*

Significant difference between snail strains for a given glycotope

!

Significant difference between LTP-treated and untreated hemocytes for a given glycotope