Figure 2.
Von Frey filament (a) and hot plate (b) response of the experimental groups. Threshold of tactile response was lower in the nontreated diabetic group as compared with the DM+DA-9801 or DM+ALA groups on the 8th week. On the 16th week, however, this trend was reversed, and the thermal response was also changed in a similar pattern to the tactile response. Data are presented as means ± SD. *P < 0.05 versus Normal and **P < 0.05 versus DM (N = 10 in each group). ALA: Alpha lipoic acid and DM: diabetes.