Table 1.

Body weight, blood glucose, blood insulin, and islet function (mean ± SD).

	WT	WH	KO	KH
Body weight (g) (beginning)	22.60 ± 0.65	22.73 ± 0.55	22.48 ± 0.33	22.56 ± 0.33
Body weight (g) (ending)	29.05 ± 0.83	34.24 ± 1.45*	29.21 ± 0.69	34.41 ± 0.69∗#
Fasting blood glucose (mmol/L)	8.18 ± 0.72	8.38 ± 0.42	8.60 ± 0.46	8.63 ± 0.55
Fasting blood insulin (ng/mL)	0.84 ± 0.02	0.97 ± 0.02*	0.87 ± 0.01	0.85 ± 0.03△
AUCI0-5 ((ng/mL) ∗ min)	9.65 ± 0.13	9.31 ± 0.06*	9.58 ± 0.15	7.40 ± 0.15∗#△
AUCI0-30 ((ng/mL) ∗ min)	43.82 ± 0.21	61.61 ± 0.56*	44.31 ± 0.31	44.93 ± 0.71△

WT: wild type mice; WH: wild type mice with high-fat diet; KO: ACE2 knockout mice; KH: ACE2 knockout mice with high-fat diet, versus WT *P < 0.05, versus KO ^# P < 0.05, and versus WH ^△ P < 0.05.