Table 1.
NGT | Pre-DM | DM | P value | Age and gender | |
---|---|---|---|---|---|
(n = 1990) | (n = 843) | (n = 304) | Adjusted P | ||
Age (year) | 54.71 ± 8.21a,c | 57.81 ± 8.50 | 58.18 ± 8.41 | <0.001 | |
Gender (male/female) | 708/1082 | 358/485 | 147/157 | <0.001 | |
BMI (Kg/m2) | 23.40 ± 2.89a,c | 24.78 ± 3.23b | 25.79 ± 3.03 | <0.001 | <0.001 |
WHR | 0.86 ± 0.67 | 0.89 ± 0.63 | 0.90 ± 630.79 | <0.001 | <0.001 |
FPG (mmol/L) | 5.35 ± 0.35a,c | 5.83 ± 0.52b | 7.45 ± 1.85 | <0.001 | <0.001 |
30 min PG | 8.52 ± 1.52a,c | 10.17 ± 1.48b | 12.82 ± 2.68 | <0.001 | <0.001 |
120 min PG | 6.04 ± 1.02a,c | 8.49 ± 1.35b | 13.89 ± 3.78 | <0.001 | <0.001 |
HbA1c (%) | 5.60 ± 0.37a,c | 5.82 ± 0.400b | 6.85 ± 1.32 | <0.001 | <0.001 |
HDL (mmol/L) | 1.39 ± 0.35a,c | 1.32 ± 0.32 | 1.29 ± 0.29 | <0.001 | <0.001 |
LDL (mmol/L) | 1.83 ± 0.75a | 2.93 ± 0.82 | 3.04 ± 0.82 | <0.001 | <0.001 |
TG (mmol/L) | 1.38 ± 0.92a,c | 1.74 ± 1.12b | 1.97 ± 1.31 | <0.001 | <0.001 |
CHOL (mmol/L) | 4.85 ± 0.96a,c | 4.99 ± 1.03 | 5.11 ± 1.03 | <0.001 | <0.001 |
SBP (mmHg) | 123.43 ± 15.40a,c | 130.58 ± 16.13b | 136.16 ± 18.89 | <0.001 | <0.001 |
DBP (mmHg) | 76.72 ± 10.13a,c | 76.69 ± 10.50b | 82.02 ± 11.70 | <0.001 | <0.001 |
baPWV (cm/s) | 1424.36 ± 272.94a,c | 1561.87 ± 330.39b | 1657.71 ± 327.62 | <0.001 | <0.001 |
INS0 | 11.60 ± 7.26 | 12.40 ± 8.52 | 13.73 ± 9.61 | <0.001 | <0.001 |
INS30 | 71.56 ± 54.28c | 71.59 ± 56.57b | 44.70 ± 40.01 | <0.001 | <0.001 |
INS120 | 48.74 ± 39.30a,c | 90.37 ± 69.90 | 89.60 ± 65.86 | <0.001 | <0.001 |
BMI: body mass index, WHR: waist-hip ratio, FPG: fasting plasma glucose, HDL: high-density lipoprotein, LDL: low-density lipoprotein, TG: triglyceride, CHOL: cholesterol, SBP: systolic blood pressure, and DBP: diastolic blood pressure.
INS0: fasting serum insulin, INS30: 30-minute serum insulin, INS120: 120-minute serum insulin, HbA1c: hemoglobin A1c, and baPWV: brachial-ankle pulse wave velocity.
aNGT versus Pre-DM, P < 0.05.
bPre-DM versus DM, P < 0.05.
cNGT versus DM, P < 0.05.