TABLE 5.

Multiple regression analysis in shiftworker, for morning- versus evening-type workers adjusting for age, body mass index, and job seniority

	Job seniority
	5–15 yrs	>15 yrs	Morning type/ evening type	Age
Global DNA methylation markers
Alu (%5mC)	β = −0.30	β = −0.86	β = 0.23	β = 0.01
	p = .20	p = .006	p = .21	p = .44
LINE-1 (%5mC)	β = 0.38	β = 0.03	β = −0.211	β = −0.012
	p = .31	p = .94	p = .47	p = .56
Gene-specific methylation markers
GCR (%5mC)	β = 1.39	β = 3.33	β = 1.10	β = 0.03
	p = .28	p = .05	p = .28	p = .65
TNF-α (%5mC)	β = 0.55	β = −0.32	β = 1.33	β = −0.064
	p = .45	p = .73	p = .02	p = .11
IFN-γ (%5mC)	β = −4.28	β = −6.50	β = −0.66	β = 0.07
	p = .02	p = .007	p = .63	p = .46