Table 1.
Patient demographics with EORTC/MSG diagnosis of aspergillosisa
| Demographic characteristic | Proven IA (n = 8) | Probable IA (n = 14) | Possible IA (n = 22) | No IFD (n = 59) |
|---|---|---|---|---|
| No. male/no. female | 5/3 | 10/4 | 15/7 | 43/16 |
| Mean age (yr) | 48.3 | 45.1 | 53.6 | 55.9 |
| Hematological malignancy (type, no.) | AML/MDS, 6; lymphoma, 1; CLL, 1 | AML/MDS, 6; ALL, 3; CML, 2; lymphoma, 1; CLL, 1; SAA, 1 | AML/MDS, 15; lymphoma, 4; ALL, 2; CML, 1 | AML/MDS, 21; lymphoma, 16; myeloma, 12; SAA, 3; ALL, 2; CML, 2; CLL, 1; other, 2 |
| HSCT (type, no.) | Allo, 2 | Allo, 9; Auto, 1 | Allo, 5 | Allo, 13; Auto, 17 |
| Disease manifestation (type, no.) | IPA, 3; IPA/sinusitis, 3; cerebral, 1; IPA/Dissem, 1 | IPA, 10; IPA/sinusitis, 1; cerebral/sinusitis, 1; IPA/Dissem, 1; IPA/cerebral/sinusitis, 1 | IPA, 16; sinusitis, 5; cerebral/sinusitis, 1 | None |
a
Abbreviations: AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia; CML, chronic myeloid leukemia; CLL, chronic lymphoblastic leukemia; MDS, myelodysplastic syndrome; SAA, severe aplastic anemia; lymphoma, Hodgkin's lymphoma, non-Hodgkin's lymphoma, lymphoproliferative disorder, and diffuse large B cell lymphoma; other, natural killer cell leukemia and chronic pancytopenia; HSCT, hematopoietic stem cell transplantation; Allo, allogeneic; Auto, autologous; IPA, invasive pulmonary aspergillosis; Dissem, disseminated disease.