Table 2.
Estimated sensitivity and specificity of the cobas HPV test for ≥CIN2 (combined phase 1 and phase 2)a
| Population | Sensitivityb |
Specificityb |
||
|---|---|---|---|---|
| % (no./total no.) | 95% CI | % (no./total no.) | 95% CI | |
| Overall (aged ≥25 years) | 88.2 (380/431) | 84.8–90.9 | 57.8 (4270/7392) | 56.6–58.9 |
| ASC-USc (aged ≥21 years) | 90 (72/80) | 81.5–94.8 | 70.5 (1056/1498) | 68.1–72.7 |
a
≥CIN2, cervical intraepithelial neoplasia grade 2 or higher; HPV, human papillomavirus.
b
Estimates of sensitivity and specificity are based on data from subjects with a valid histologic diagnosis from CPR. CI, confidence interval.
c
ASC-US, atypical squamous cells of undetermined significance.