Table 1.

Multiple infection DNA positivity and multiple high viral loads with all 54 HPV (sub)types or 14 Hr-HPV in the Belgian screening population stratified by age

HPV type	Age group (yr)a	HPV-negative (n)	DNA positivity						High load						Total samples (n)
			Single infection		Multiple infection		Overall frequency (%)b	Multiple infections vs all DNA positives (%)	Single infection		Multiple infection		Overall frequency (%)b	Multiple infections vs all high loads (%)
			n	%	n	%			n	%	n	%
54 HPV (sub)types	15–24	44	27	27.3	28	28.3	55.6	50.9	20	20.2	11	11.1	31.3	35.5	99
	25–34	133	46	19.7	54	23.2	42.9	54.0	35	15	24	10.3	25.3	40.7	233
	35–44	186	50	18.6	33	12.3	30.9	39.8	20	7.4	12	4.5	11.9	37.5	269
	45–54	133	42	20.9	26	12.9	33.8	38.2	18	9.0	7	3.5	12.4	28.0	201
	55–64	84	30	22.9	17	13.0	35.9	36.2	12	9.2	2	1.5	10.7	14.3	131
	≥65	46	12	18.5	7	10.8	29.2	36.8	7	10.8	1	1.5	12.3	12.5	65
	Total	626	207	20.7	165	16.5			112	11.2	57	5.7			998
14 Hr-HPV	15–24	59	24	24.2	16	16.2	40.4	40.0	16	16.2	4	4.0	20.2	20.0	99
	25–34	151	51	21.9	31	13.3	35.2	37.8	30	12.9	12	5.2	18.0	28.6	233
	35–44	214	37	13.8	18	6.7	20.4	32.7	14	5.2	4	1.0	6.7	22.2	269
	45–54	152	39	19.4	10	5.0	24.4	20.4	14	7.0	2	1.0	8.0	12.5	201
	55–64	102	21	16.0	8	6.1	22.1	27.6	5	3.8	1	0.8	4.6	16.7	131
	≥65	51	10	15.4	4	6.2	21.5	28.6	4	6.2	0	0.0	6.2	0.0	65
	Total	729	182	18.2	87	8.7			83	8.3	23	2.3			998

^aFor one patient in the screening population, no age information was available.

^bOverall frequency is the number of HPV positives to the number of all samples, expressed as a percentage.