Table 1.
Performance of the illumigene group A Streptococcus assay compared to that of the standard culture
| Clinical test site no. | No. of specimens tested | Results (no.)a |
Performance (% [95% CI])b |
||||||
|---|---|---|---|---|---|---|---|---|---|
| TP | FP | TN | FN | Sensitivity | Specificity | PPV | NPV | ||
| 1 | 338 | 40 | 11 | 287 | 0 | 100 (91–100) | 96.3 (93–98) | 78.4 (64–88) | 100 (98–100) |
| 2 | 241 | 18 | 18 | 205 | 0 | 100 (81–100) | 91.9 (87–95) | 50 (32–67) | 100 (98–100) |
| 3 | 217 | 16 | 13 | 188 | 0 | 100 (79–100) | 93.5 (89–96) | 55.2 (35–73) | 100 (98–100) |
| Total | 796 | 74 | 42 | 680 | 0 | 100 (95–100) | 94.2 (92–95) | 63.8 (54–72) | 100 (99–100) |
a
TP, true positive; FP, false positive; TN, true negative; FN, false negative.
b
CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value.