Fig 1.

Dendrogram of PFGE profiles of 66 S. epidermidis isolates causing CRBSI (n = 33) or collected from the skin of healthy volunteers (n = 33). For each isolate represented, the year of isolation and the presence of the mecA gene, the ica operon, and the ACME are listed, as well as the number of cases of resistance observed, the MLST ST (when tested), and the SCCmec type (mecA-positive isolates). Additionally, for isolates causing CRBSI, severe clinical presentation, hospitalization unit, and attributable death are indicated. PFGE types shared by CRBSI and commensal isolates are represented in boldface. Abbreviations: HV, healthy volunteer; G, gastrointestinal surgery units; H, hematology unit; ICU, intensive care units; N-U, nephrology-urology units; P, pulmonary oncology. *, close to ST86; **, close to ST19; °, number of cases of resistance observed among the 12 non-β-lactam antimicrobials tested (Table 1).