Fig 8.

Influence of indomethacin and betamethasone treatment on human T cell population in GBS-infected humanized mice. Humanized mice were infected with a moderate dose (1 × 10⁶ CFU) of GBS and treated twice (24 and 48 h) with betamethasone (n = 9), indomethacin (n = 6), or vehicle alone (PBS: n = 8). On day 3, mice were sacrificed and CD4 and CD8 T cell populations in the spleen were analyzed. Significant differences were calculated using 1-way ANOVA: A*, P < 0.05; A**, P < 0.01. In addition, significant differences between different treatment groups were calculated using Tukey's multiple comparison test: *, P < 0.05; **, P < 0.01.