Table 1.

Prevalence, 95% confidence intervals, and mean fluorescence intensity of IgG responses to each fragment of P. vivax MSP1P, MSP1-19, and DBPII in human patients and healthy individual serum samples

Antigen	No. of patient samples			95% CIb	MFIc	No. of healthy samples			95% CI	MFI	P valuee
	Positive	Negative	Total (%)a			Positive	Negative	Total (%)d
MSP1-19	120	30	150 (80.0)	67.6–82.5	15,573	6	94	100 (94.0)	90.0–97.8	3,122	P < 0.0001
DBPII	95	55	150 (63.3)	55.7–70.8	9,176	4	96	100 (96.0)	90.1–98.4	3,126	P < 0.0001
83Af	75	75	150 (50.0)	42.1–57.9	6,193	5	95	100 (95.0)	88.8–97.8	2,033	P < 0.0001
83Bf	11	39	50 (22.0)	12.8–35.2	3,796	3	37	40 (92.5)	80.1–97.4	2,599	P = 0.03
83Cf	12	38	50 (24.0)	14.3–37.4	3,807	3	37	40 (92.5)	80.1–97.4	2,782	P = 0.04
30f	22	28	50 (44.0)	31.1–57.7	4,100	1	39	40 (97.5)	87.1–99.6	2,291	P = 0.0003
38f	12	38	50 (24.0)	14.3–37.4	4,288	1	39	40 (97.5)	87.1–99.6	3,159	P = 0.03
42f	16	34	50 (32.0)	20.7–45.8	5,408	2	38	40 (95.0)	83.8–98.6	3,216	P = 0.001
33f	90	60	150 (60.0)	52.0–67.5	4,015	4	96	100 (96.0)	90.1–98.4	1,384	P < 0.0001
19f	102	48	150 (68.0)	60.1–74.9	5,878	4	96	100 (96.0)	90.1–98.4	2,033	P < 0.0001

^aSensitivity: percent positive in patient samples.

^bCI, confidence interval.

^cMFI, mean fluorescence intensity.

^dSpecificity: percent negative in healthy samples.

^eDifferences in the total IgG prevalence for each antigen between vivax patients and healthy individuals were calculated with Student's t test. A P value of <0.05 is considered statistically significant.

^fPvMSP1P fragments used as capture antigens.