Table 1.
Mixture | Haplotype no.a | Coverage (%) |
|
---|---|---|---|
Minimumb | Meanc | ||
Minimum bestd | 9, 13, 20, 31, 106 | 83.6 | 94.5 |
Mean beste | 7, 15, 58, 87, 106 | 74.9 | 98.1 |
5 allelesf | 2, 6, 20, 21, 105 | 83.6 | 98.1 |
4 allelesg | 2, 6, 20, 105 | 74.9 | 96.5 |
Haplotype numbers are the numbers in Fig. S2 in the supplemental material.
The lowest coverage of haplotypes in unselected 103/102 haplotypes by the 4-/5-allele-mixture vaccines.
The mean coverage of the unselected 103 or 102 haplotypes by the 4- or 5-allele-mixture vaccines, respectively.
The best mixture of haplotypes was selected from 107 haplotypes of AMA1 on the basis of the minimum coverage of key amino acid sites.
The best mixture of haplotypes was selected from 107 haplotypes of AMA1 on the basis of the mean coverage of key amino acid sites.
The 5-allele-mix vaccine used in this study.
The 4-allele-mix vaccine used in this study.