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Viable, cultivable spirochetes lacking dbpBA are recovered from tissue in increasing frequency over time in immunocompetent C3H mice
| Isolate genotype | Day | No. of positive cultures/total |
No. of positive mice/total | |
|---|---|---|---|---|
| Subinoculation site | Bladder | |||
| ΔdbpBA | 14 | 2/5 | 0/5 | 2/5 |
| 28 | 4/5 | 0/5 | 4/5 | |
| 42 | 4/5 | 4/5a | 4/5 | |
| Wild type | 14 | 5/5 | 2/4 | 5/5 |
| 28 | 5/5 | 5/5 | 5/5 | |
| 42 | 5/5 | 1/5 | 5/5 | |
In 3 of the 4 positive cultures, spirochetes were observed only rarely.
