Genetic organization of the K. oxytoca
gat-tag genes encoding a PTS-dependent d-tagatose pathway, of the B. licheniformis five-gene cluster encoding a d-tagatose pathway, and of B. smithii and B. cereus genes encoding hypothetical d-tagatose pathways. The regions enclosing the genes coding for class II tagatose-bisphosphate aldolase (gatY) and neighboring genes are shown. The dashed arrow shows genes not implicated in a d-tagatose pathway. orf80 to orf87 are locus tags HMPREF1015_01180 to HMPREF1015_01187 in the genome of B. smithii 7_3_47FAA. G 6-P isomerase sub A and sub B are the subunits of the galactose 6-P isomerase. IIA, IIB, and IIC are predicted products of the sugar-specific PTS system. orf75 to orf84 are locus tags IGC_03675 to IGC_03684 of the B. cereus HuA4_10 genome. Nag 6-P deacetylase is a putative N-acetylglucosamine 6-P deacetylase. orf75 encodes a putative transcriptional regulator/sugar kinase, NagC.