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Phylogenetic tree based on pagC sequences from 34 pathogenic E. coli strains. pagC sequences were aligned, and a tree was constructed using the maximum-likelihood method with 2,000 iterations utilizing MEGA 5.05 (26). pagC sequences from eae-negative STEC are marked in boldface italic type, and eae-positive STEC strains were marked in boldface regular type. pagC genes sequenced in this study are marked by black frames. EPEC, enteropathogenic E. coli; ETEC, enterotoxigenic E. coli.
