Table 1.
HIV status and group | No. of subjects | Mean CD4 count (/mm3) | Mean viral load (no. of copies/ml) | No. of responders against APOBEC3 pool | Mean APOBEC3 pool response (no. of SFU/106 PBMC)a | Range of APOBEC3 pool responses (SFU/106 PBMC)a | % of responders |
---|---|---|---|---|---|---|---|
HIV infected | |||||||
Chronic infection | |||||||
LTNPb | 7 | 828 | 117 | 5 | 486 | 0–2,480 | 71 |
Natural controllers | 19 | 643 | 393 | 6 | 45 | 0–285 | 32 |
HAART suppressed | 20 | 626 | 51 | 8 | 54 | 0–250 | 40 |
Viremic | 21 | 282 | 52,656 | 3 | 34 | 0–290 | 14 |
Primary infection | 13 | 673 | 13,435 | 6 | 84 | 0–305 | 46 |
Children with chronic infection | 73 | 836 | 18,488 | 13 | 88 | 0–1,780 | 18 |
HIV-exposed children but uninfected | 7 | 0 | 5 | 0–35 | 0 | ||
Nonexposed, healthy HIV-negative adults | 33 | 2 | 18 | 0–210 | 6 |
SFU, spot-forming units. The background SFU have been subtracted from the values shown.
LTNP, long-term nonprogressors.