Table 1.

Ten cellular miRNAs most activated/repressed by HPV-31 in organotypic raft cultures^a

Rank	High in viv	Fold difference	High in viv-31gen	Fold difference
1	hsa-miR-582-3p	9.185	hsa-miR-1246	31.693
2	hsa-miR-199a-5p	8.668	hsa-miR-335*	10.612
3	hsa-miR-214	8.432	hsa-miR-1260b	8.691
4	hsa-miR-143	7.278	hsa-miR-3613-5p	5.855
5	hsa-miR-145	7.096	hsa-miR-1260	4.6
6	hsa-miR-145*	6.894	hsa-miR-1285	4.111
7	hsa-miR-369-3p	6.522	hsa-miR-576-5p	4.015
8	hsa-miR-655	6.377	hsa-miR-615-5p	3.921
9	hsa-miR-493	6.211	hsa-miR-92b	3.692
10	hsa-miR-493*	5.318	hsa-miR-25*	3.316

^aA small RNA population was isolated using a Roche small RNA isolation kit, and small RNA libraries were made using the Illumina small RNA library kit. Solexa deep sequencing of the libraries was performed. The resulting miRNAs were refined by using a threshold of at least 100 reads and a fold difference of at least 2. High in viv, having increased levels in viv normal keratinocytes compared to HPV-31-positive cells; high in viv-31gen, having increased levels in HPV-31-positive cells compared to viv normal keratinocytes.