Fig 5.

Neutralization sensitivity to monoclonal antibodies. Neutralization sensitivity of the SIVmac251 T/F Env clone PBE (27, 41) (A), the SIVmac239 clone (B), or the uncloned SIVsmE660 isolate (C). IC₅₀ titers for the uncloned SIVsmE660 isolate, isolate Env clones, and T/F Env clones of selected MAbs (D). Clone designation (x axis) and color coding correspond to Fig. 2. Results represent the means (A, B, and D) or mean ± SD (C) for at least three independent neutralization experiments in the TZM-bl assay.