Table 2.
Replication of H7 influenza viruses following ocular inoculation in mice
| Tissue | Day p.i. | Virus titera |
||
|---|---|---|---|---|
| rk/NJ/06 | gs/NE/11 | MX/7218 | ||
| Eye | 3 | <0.8 | 2.5 (1/3) | 3.4 ± 1.2 (2/3) |
| Nose | 3 | <0.8 | <0.8 | 2.9 ± 0.5 (2/3) |
| Lung | 3 | <0.8 | <0.8 | <0.8 |
| Eye | 6 | <0.8 | 2.4 ± 1.0 | 3.4 ± 0.6 |
| Nose | 6 | <0.8 | 2.2 ± 0.4 | 3.3 ± 0.7 (2/3) |
| Lung | 6 | 1.5 (1/3) | <0.8 | 2.75 (1/3) |
a
Mean virus titers in mice inoculated with 106 EID50/5 μl of virus following corneal scarification. Virus titers are expressed as the mean log10 EID50/ml ± standard deviation among mice with positive virus detection (data are representative of all mice examined, unless denoted in parentheses, in which the number of mice with positive virus detection/total number of mice in the group are indicated). The limit of virus detection was 100.8 EID50/ml.