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. 2013 May 8;8(5):e63731. doi: 10.1371/journal.pone.0063731

Figure 4. Huaier inhibited the migration of ovarian cancer cells in vitro, as measured in a scratch assay.

Figure 4

(A) A straight wound area was generated in each culture well at the beginning, and administration of Huaier (5 mg/ml) showed a delayed process of wound closure compared with the untreated cells. Representative images of the control cells and 5 mg/mL Huaier-treated cells were acquired at 0, 12,24 h (SKOV3, SKOV3.ip1) or 0, 6, 12 h (Hey). (B) The migration indices were significantly inhibited by Huaier. The bars represent the migration index for each treatment, expressed as a value relative to the distance moved by the cell monolayer. The data are presented as means ± SD. The experiments were repeated at least three times. ** p<0.01 compared with the control.