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(A) Huaier treatment altered the transcription of DIDX2, LRP6 and Wnt 5A genes in the SKOV3, SKOV3.ip1 and Hey cells. The gene expression was measured by real-time PCR in cells treated with 7.5 mg/ml Huaier for 48 h, and untreated cells served as the control. (B) Cyclin D1 protein expression was suppressed after treatment with 5 mg/ml and 7.5 mg/ml Huaier for 24, 48 and 72 h in three cell lines.
