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. 2013 May 4;13:225. doi: 10.1186/1471-2407-13-225

Table 3.

Adjusted HRs of all-cause mortality associated with race (black women vs. white women)

 
White
Black
Model 1a
Model 2a,b
  Person-years Death (No.) Person-years Death (No.) HR 95% CI HR 95% CI
All women
6246
155
4471
180
1.65
1.32 to 2.06
1.42
1.13 to 1.78
Subtypes defined by ER/PR/HER2
 
 
 
 
 
 
 
 TN
1341
50
1381
66
1.25
0.85 to 1.84
1.12
0.76 to 1.66
 Luminal A
3853
75
2235
70
1.75
1.25 to 2.46
1.54
1.09 to 2.18
 Luminal B
643
16
481
16
1.74
0.70 to 4.31
1.07
0.32 to 3.53
 HER2-enriched
408
14
375
28
2.69
1.06 to 6.85
2.41
0.90 to 6.40
Subtypes defined by ER/PR/HER2/p53
 
 
 
 
 
 
 
 TN/p53-
825
26
664
34
1.45
0.82 to 2.54
1.38
0.77 to 2.49
 TN/p53+
516
24
717
32
1.04
0.58 to 1.88
1.04
0.57 to 1.89
 Luminal A/p53-
3262
55
1814
52
1.73
1.16 to 2.58
1.62
1.08 to 2.43
 Luminal A/p53+
591
20
421
18
1.45
0.60 to 3.54
0.99
0.37 to 2.70
Younger women (ages 35–49 yrs)
3066
90
2248
95
1.49
1.10 to 2.01
1.27
0.94 to 1.73
Subtypes defined by ER/PR/HER2
 
 
 
 
 
 
 
 TN
861
34
785
43
1.36
0.84 to 2.18
1.16
0.71 to 1.89
 Luminal A
1623
36
1069
28
1.33
0.79 to 2.23
1.20
0.71 to 2.03
Subtypes defined by ER/PR/HER2/p53
 
 
 
 
 
 
 
 TN/p53-
513
18
372
21
1.44
0.72 to 2.87
1.43
0.70 to 2.90
 TN/p53+
349
16
413
22
1.21
0.60 to 2.47
1.13
0.54 to 2.36
 Luminal A/p53-
1329
28
792
17
1.06
0.56 to 2.01
1.05
0.54 to 2.02
 Luminal A/p53+
294
8
277
11
1.32
0.32 to 5.42
0.92
0.21 to 4.06
Older women (ages 50–64 yrs)
3181
65
2223
85
1.89
1.36 to 2.62
1.62
1.17 to 2.26
Subtypes defined by ER/PR/HER2
 
 
 
 
 
 
 
 TN
480
16
596
23
1.04
0.54 to 2.02
1.07
0.55 to 2.11
 Luminal A
2231
39
1167
42
2.21
1.40 to 3.47
1.88
1.18 to 2.99
Subtypes defined by ER/PR/HER2/p53
 
 
 
 
 
 
 
 TN/p53-
313
8
292
13
1.66
0.61 to 4.54
1.48
0.50 to 4.41
 TN/p53+
167
8
304
10
0.77
0.27 to 2.20
0.79
0.27 to 2.30
 Luminal A/p53-
1934
27
1022
35
2.49
1.47 to 4.22
2.22
1.30 to 3.79
 Luminal A/p53+ 297 12 144 7 1.54 0.48 to 4.91 1.44 0.25 to 8.11

HRs are from multivariable Cox proportional hazards regression models using age (in days) at diagnosis and at death or end of follow-up as the time scale and stratified by single years of age at diagnosis. aAdjusted for study site. bAdditionally adjusted for tumor stage. Abbreviations: HR, hazard ratio; CI, confidence interval. ER, estrogen receptor; PR, progesterone receptor; HER, human epidermal growth factor receptor; TN, triple negative. Note: TN = ER-/PR-/HER2-, Luminal A = ER+ or PR+ plus HER2-, Luminal B = ER+ or PR+ plus HER2+, HER2-enriched = ER-/PR-/HER2+.