Table 2. Survival analysis.

	Univariate		Multivariate
Parameter	HR	p-value	HR	p-value
TN	2.83	4.9*10−7	1.72	0.06
Grade 3 vs. 1 or 2	1.57	0.03	0.87	0.55
Stage III vs. IIA or IIB	2.42	1.5*10−5	1.58	0.05
Age >50	1.03	0.89	1.02	0.91
Lymph node positivevs. negative	3.16	4.2*10−5	2.17	0.02
PC1a>median PC1a	0.86	0.69	0.87	0.73
PC2a>median PC2a	0.69	0.08	0.91	0.66
PC3a>median PC3a	1.81	0.003	1.75	0.01
PC4a>median PC4a	0.364	7.3*10−6	0.52	0.02
PC5a>median PC5a	1.22	0.33	1.21	0.36
PC6a>median PC6a	1.61	0.02	1.30	0.21

A Cox proportional hazard model demonstrated that the third and fourth principal components had significant effects on survival of patients, even when accounting for clinical variables.