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. 2013 May 8;8(5):e61405. doi: 10.1371/journal.pone.0061405

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© 2013 Bhargava et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Lung CXCL1 (a neutrophil chemokine), and (B) lung MPO activity (a biochemical indicator of lung neutrophils) were measured 4 hours after AKI (indirect lung injury), IP endotoxin (indirect lung injury), and IT endotoxin (direct lung injury) in mice treated with 200 ng of IT IL-6 or IT vehicle (veh) (0.1% BSA) 30 minutes prior to injury (n = 5–7).