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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: J Cardiovasc Pharmacol. 2013 May;61(5):369–377. doi: 10.1097/FJC.0b013e318285f55b

Figure 2.

Figure 2

The sarcKATP channel in mouse ventricular cardiomyocytes. (A) Single channel activity was monitored in the inside-out patch configuration at Em +40 mV in the absence (Control) or presence of sarcK channel blocker HMR-1098. (B) HMR-1098 (30 μM) inhibited channel activity by 97%. Data are mean±SEM, n=8. (C, D) No channel activity was detected in membrane patches excised from Kir6.2 KO myocytes when monitored in control conditions or during application of channel opener pinacidil (100 μM), n=7.