. Author manuscript; available in PMC: 2014 May 1.

Published in final edited form as: J Cardiovasc Pharmacol. 2013 May;61(5):401–407. doi: 10.1097/FJC.0b013e31828748ca

Table 1.

Electrophysiologic effects of SIN-1 in cardiac myocytes

Ventricle (n=6, N=3)	Control	SIN-1	P value
I_k1 at -100mV(pA/pF)	-6.552 ±1.911	-6.584 ± 0.548	0.185
I_K1 Peak Outward (pA/pF)	1.774 ± 0.127	1.688 ± 0.214	0.393
I_to at +50 (pA/pF)	7.143 ±1.664	6.803 ±1.585	0.003
I_kr Peak (pA/pF)	1.533 ± 0.147	1.502 ± 0.115	0.365

Atria (n=8, N=3)	Control	SIN-1	P value
I_k1 at -80mV (pA/pF)	-0.328 ± 0.264	-0.239 ± 0.306	0.348
I_to at +50mV (pA/pF)	5.842±0.654	5.206± 0.775	0.597
I_ksus (pA/pF)	6.271 ± 0.926	5.834 ± 1.088	0.326

I_K1 (inward rectifier potassium current), I_to (transient outward potassium current), I_Kr (fast component of the delayed rectifier potassium current), I_Ksus (sustained outward potassium current which contains I_Kur, I_Ks and I_Kr), n (number of cells per group), N (number of animal per group)