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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Prog Retin Eye Res. 2013 Feb 5;35:18–43. doi: 10.1016/j.preteyeres.2013.01.004

Figure 3.

Figure 3

Proteomics studies towards molecular mechanisms and biomarkers of glaucoma. A number of studies of human glaucoma and in vitro and in vivo experimental models have used proteomics analysis techniques. Distinct proteomics techniques have been applied to analyse diverse sample types, including optic nerve, retina, sclera, trabecular meshwork, aqueous humor, pseudoexfoliative material, tear, and blood. Ocular samples included tissue lysates unless indicated otherwise, such as cell cultures or enriched samples of RGCs or astrocytes. Blood samples included whole serum, IgG elutes, or isolated leukocytes. * indicates the studies including human samples. Proteomics analysis of glaucoma has resulted in the lists of differentially expressed proteins and contributed to current understanding of molecular mechanisms and biomarkers of glaucoma.