Table 4.
Comparison of RET/PTC or PAX8/PPARγ positive tumors with BRAF or RAS mutation positive tumors according to selected patient characteristics in thyroid cancers that developed after the Chernobyl accident
| Characteristic | Relative risk of rearrangements vs point mutations (95% CI) |
P heterogeneity1 | |
|---|---|---|---|
| I-131 dose, Gy | 8.00 (1.30, 150.96) | 0.020 | |
| Oblast of residence | Kyiv vs Chernihiv | 4.12 (0.22, 100.89) | 0.003 |
| Zhytomyr vs Chernihiv | 139.07 (7.13, 5843.00) | ||
| Age at surgery, yr | 0.62 (0.47, 0.79) | <0.001 | |
| Sex | Female vs Male | 0.01 (0.00, 0.16) | <0.001 |
1
Based on multivariate logistic regression models.